He started his journalism career as a sports and feature writer in San Diego, freelancing for the San Diego Union-Tribune and San Diego Magazine (1980-1982). He did this after working as a staff writer or the Times-Advocate (now the North County Times) in Escondido, Calif. (1978-80)
From 1982-89, Keteyian worked as a writer for Sports Illustrated. He then joined NBC Sports as a reporter and producer. In 1989, he joined ABC News as a correspondent; he contributed stories to World News Tonight with Peter Jennings. In 1997, he joined CBS Sports as a reporter where he contributes to the network's NCAA college basketball and NFL telecasts. In addition to his CBS Sports duties, Keteyian is also a correspondent on the HBO newsmagazine, Real Sports with Bryant Gumbel. At the end of the 2005 NFL season, Keteyian left his work as a sideline reporter to work as the chief investigative reporter for CBS News.
Keteyian is the recipient of eight Emmy Awards, including four for CBS Sports, three for coverage of the Tour de France (2002-04) and one for a Super Bowl pre-game piece about NFL quarterbacks and their sons (2005). He also has two Sports Journalism Emmys for "Real Sports" — a report on the financing of Bank One Ballpark, now Chase Field, in Phoenix, Arizona (1998) and a story on high school basketball star Amare Stoudemire (2001). Keteyian also has written or co-written nine books including the New York Times best-seller Why You Crying?, the biography of comedian-actor George Lopez.
He lives in New Canaan, Connecticut with his wife Dede and two daughters.