Karen Karapetian may refer to:
- Karen Karapetian (1963) - former mayor of Yerevan, December 2010 to October 2011, and later Prime Minister from September 2016 to April/May 2018.
- Karen Karapetyan (1961) - member of parliament.
There is a former presidential chief of his staff for Serzh Sarkisan until October 2011 that is named Karen Karapetian. Not clear if he is the same as the member of parliament.
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